If you're using the Mega Jumping Game Genie code (YEUKOTGA) you can jump right over the Large Snake Heads.
If you want these power ups, you'll have to get them now.
Jumping across this pit can be difficult. Jump at the last second and Mega Man will land safely.
Wait until these Cloud Platforms reach the top of the screen before you jump, you'll need all the help you can get to land safely on the next "solid" platform.
Shooting the Cloud Missile will make it angry, but this can be used to an advantage. After being hit, the Cloud Missiles travel in a straight line rather than floating randomly, also they speed up. Jump over the Missile as it comes towards you.
Again, firing on a Cloud Missile will make it fly in a straight line, so use it to your advantage, jump right over as it comes flying by.
Look at Snake Man, he's got a little smirk... like he thinks he's better than Mega Man - let's set him straight!
If you don't have the Needle Cannon yet, use the Spark Shock. Note: Spark Shock runs out very quickly, so use it only when you know you have a good shot.
Personally I like the Needle Cannon against Snake Man. Not only does it cause a lot of damage, but it's very efficient- you can shoot hundreds of these before they run out. Also, it's got Auto-Fire!
Destroying Snake Man will earn you his Search Snakes... very useful against the final Dr. Wily (hint, hint).