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If you're using the Mega Jumping Game Genie code (YEUKOTGA) you can jump right over the Large Snake Heads.
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If you want these power ups, you'll have to get them now.
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Jumping across this pit can be difficult. Jump at the last second and Mega Man will land safely.
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Wait until these Cloud Platforms reach the top of the screen before you jump, you'll need all the help you can get to land safely on the next "solid" platform.
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Shooting the Cloud Missile will make it angry, but this can be used to an advantage. After being hit, the Cloud Missiles travel in a straight line rather than floating randomly, also they speed up. Jump over the Missile as it comes towards you.
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Again, firing on a Cloud Missile will make it fly in a straight line, so use it to your advantage, jump right over as it comes flying by.
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Look at Snake Man, he's got a little smirk... like he thinks he's better than Mega Man - let's set him straight!
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If you don't have the Needle Cannon yet, use the Spark Shock. Note: Spark Shock runs out very quickly, so use it only when you know you have a good shot.
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Personally I like the Needle Cannon against Snake Man. Not only does it cause a lot of damage, but it's very efficient- you can shoot hundreds of these before they run out. Also, it's got Auto-Fire!
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Destroying Snake Man will earn you his Search Snakes... very useful against the final Dr. Wily (hint, hint).